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In Vitro Fertility Goddess Excerpt

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Back at work after the failed conception trip to Paris, one thing I seem unable to avoid is Fertility Goddess workmates.

There used to be one on a flight per week, but all of a sudden there seems to be at least one on every flight.

Is like lambing season in the air, with protruding stomachs wherever you look. The main culprit (besides the husbands) is the Olympic Games which are fast approaching and nobody wants to fly during them. Girls have actually postponed/timed their families around the event to avoid it!

And worse, they've succeeded. The joke is that the maternity uniform is actually the official Olympic uniform. Almost every flight I find myself working with a pregnant fertility goddess and the most annoying attribute is their perception that because they are glowingly pregnant everyone else must be pregnant or at least trying.

Worse, the ones who know I've been to Paris get all ‘nudge, nudge, wink, wink' with me, throwing meaningful glances at my stomach and making comments like "Oh Paris is the city of lurve. My friend went there and it was so romantic she got pregnant!"

What do they think, the sight of the Eiffel Tower and all that Haussman architecture turns you into rabbits bonking day and night for weeks on end?

And, like women in the newly engaged state who are incapable of discussing anything but wedding dresses and engagement rings, these pregnant women are incapable of talking about any topic save for ultrasounds and baby names. Is totally excruciating!

This morning I was on the end of a trolley with one such girl and by about halfway through handing out the trays, was practically at the point of forcibly opening an aircraft door mid-flight and getting self sucked into the upper atmosphere. The morning sickness, the cravings, the veins, on it went. Then she interrupted herself to throw in,

‘Oh, what about you then? You've been married for years now, when are you going to have a baby?"

With every bit of self-control I could find, I stopped myself just in time from inducing an aisle birth by way of trolley.

"Actually I just lost one, miscarriage, you know."

She went slightly green but it could have been her morning sickness.

There, I'd said it. Shouted it, actually, at thirty-nine thousand feet. The entire rear of the plane simultaneously looked up from their turkey rissoles and this was strangely liberating. Back in the galley the no-longer-smug girl apologised and the other girls went all quiet and seemed to whisper for the rest of the flight.

Later as we were leaving the aircraft a non-pregnant girl attached herself to my side and confessed that she too had had a miscarriage last year and I was the first person she'd told outside of immediate family.

"What is it, why don't we talk about it? It's like there's a hidden code of silence or something. I've never in ten years of working here heard of one miscarriage. And I've heard all about every birth."

"They're all proud of their births, nobody's proud of having miscarriage."

"But we don't deliberately cause our miscarriages."

What was wrong with women that they felt so ashamed to talk about their reproductive failings and so compelled to flaunt their fertility to each other?
 

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Miscarriage Cure?

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Wednesday 10 September 2008

Source: Human Reproduction

A new scientific breakthrough has the potential to prevent millions of unexplained miscarriages worldwide after the discovery that up to a third of them are caused by an excess of immune cells in a woman's uterus.

Researchers in Britain will soon start trials involving a steroid drug which will be administered to women who have suffered recurrent miscarriages.

Professor Siobhan Quenby from the school of reproductive and developmental medicine at Liverpool University who led the study says the treatment should be able to prevent up to 3000 miscarriages a year in the UK alone once it's available to patients in 5 to 10 years time.

Professor Quenby also hopes to develop a screening test to determine if certain women are at risk of miscarriage before they fall pregnant.

30 out of 40 of her patients who were suffering from multiple miscarriages have already given birth to healthy babies after receiving the steroid drug called prednisolone.

The research focused on the discovery of a link between excess blood supply and the failure of a foetus to implant in the womb which is thought to be caused by a type of immune system cell in the womb that promotes the growth of blood vessels.

This in turn creates an over supply of blood and oxygen undermining the foetus' ability to become implanted into the wall of the womb, leading to miscarriage.

But leading fertility expert Professor Lord Robert Winston warned that it was difficult to know how affective the treatment is until a full clinical trial had been completed.

He said: "It is a very important area, but a difficult one. There is always the chance of this being caused by the placebo effect."

Sarah Williams, IVFG Reporter



Infertile Women Can Regain Their Fertility

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Tuesday 17 March, 2009

Source: Society for Endocrinology BES

A recently discovered hormone could help infertile women regain their fertility.

It's called kisspeptin and British scientists believe that this protein can stimulate the release of reproductive hormones which control the menstrual cycle.

Kisspeptin and the gene that serves as its blueprint, KISS-1, is produced during adolescence and triggers the release of the hormones that bring on puberty. In animals, kisspeptin has been shown to play a role in reproduction too where lower production levels of kisspeptin triggers the loss of reproductive urges. Animals and humans lacking kisspeptin do not go through puberty and remain sexually immature.

Lead researcher Dr Waljit Dhillo from Imperial College London studied 10 women who were not menstruating and were infertile. The women were then injected with either kisspeptin or a placebo.

Blood samples were taken to measure levels of the luteinising hormone and follicle stimulating hormone, both of which are crucial for ovulation and fertility.

Kisspeptin led to a 48-fold increase of luteinising hormone and a 16-fold increase in follicle stimulating hormone compared with the inactive salt solution.

The study is the first to show that kisspeptin can stimulate sex hormones in women suffering from infertility and confirms earlier research that the treatment leads to the production of sex hormones in fertile women.

Sarah Williams



UK fertility clinics asked to use single embryo transfer

Wednesday 3 September, 2008

Source: British Fertility Society  

Experts from the British Fertility Society and the Association of Clinical Embryologists have called on fertility clinics to mainly use single embryos for women younger than 37 to reduce a rate of multiple births.

The call is aimed at helping Britain's fertility clinics to meet the Human Fertilisation and Embryology Authority's three-year target to cut multiple pregnancy rates by more than half over the next three years. Currently, there were 11,262 children born through IVF treatment last year of whom 4,000 were twins.

Multiple pregnancies and births are the single biggest risk for women during fertility treatment because they increase the likelihood of premature birth miscarriage, long-term health problems for the child and can also endanger the mother's health.
                            
Out of the more than 3.5 million babies born worldwide using assisted reproductive technology in the past 30 years, most since have been born to women aged between 30 and 39.

The move for single embryo implantation in Britain follows is not an isolated case as some European governments have already legislated to outlaw multiple implants reduce pregnancy risks.
                            
The HFEA wants women younger than 37 who produce high quality embryos to only receive a single transfer during their first cycle and to freezed the other embryos for use later.

Sarah Williams, IVFG Reporter





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